Key findings from the Neurokinex trial of the Onward Medical ARC-ex device

The Neurokinex-led Pathfinder2 Study, sponsored by Spinal Research and published in Neuromodulation: Technology at Neural Interface on February 25, 2025, represents a landmark investigation into the long-term efficacy of ONWARD Medicalʼs ARC-EX Therapy for spinal cord injury (SCI) rehabilitation. This one-year trial demonstrated sustained functional improvements in chronic SCI patients, challenging historical assumptions about recovery plateaus and redefining expectations for neurorehabilitation outcomes.

Transcutaneous spinal cord stimulation delivers electrical currents through surface electrodes positioned over the spinous processes, modulating spinal circuit excitability. Unlike invasive epidural stimulation, tSCS non-invasively targets dorsal roots and interneuronal networks, facilitating neuromodulation of both ascending sensory and descending motor pathways. The stimulation parameters (typically 30-50 Hz) are designed to enhance residual supraspinal connectivity while activating latent central pattern generators (CPGs) responsible for rhythmic motor outputs. Recent studies suggest that tSCS amplifies sensorimotor integration, enabling volitional movement by lowering activation thresholds for preserved neural pathways.

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How does the timing and intensity of stimulation in home-based FES (hbFES) affect the structural recovery of lower motor neurons and muscle fibres following a complete denervation injury?

Home-based functional electrical stimulation (hbFES) is revolutionizing the treatment of complete lower motor neuron denervation injuries. Once considered an inevitable path to muscle deterioration, new research and clinical evidence show that properly timed and calibrated electrical stimulation can not only preserve muscle tissue but actually promote structural recovery. At Anatomical Concepts, we work with the RISE Stimulator from Schuhfried Medizintechnik GmbH, enabling clients to take control of their rehabilitation journey from home. This innovative approach has demonstrated remarkable results, including significant increases in muscle cross-sectional area and force output, challenging long-held assumptions about the irreversibility of denervation effects.

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FES Cycling, rehabilitation Derek Jones FES Cycling, rehabilitation Derek Jones

FES Cycling vs. Passive Movement Training: The Pros and Cons

In the world of neurorehabilitation, two approaches have emerged as prominent tools for helping patients regain mobility and function: Functional Electrical Stimulation (FES) Cycling and Passive Movement Training (PMT). While both have their place in rehabilitation settings, understanding their distinct benefits and limitations is crucial for healthcare professionals and patients alike. PMT, utilising motorized bikes like the Thera or MOTOmed, has long been a staple in hospitals and homes due to its ease of use and accessibility. However, the integration of electrical stimulation in FES Cycling has opened new doors in rehabilitation, particularly for those with spinal cord injuries, stroke, cerebral palsy, and multiple sclerosis. With over three decades of research backing its efficacy, FES Cycling represents a significant advancement in rehabilitation technology – but what makes it truly different from traditional PMT, and why should clinicians and patients take notice? Let's delve into the science behind these approaches and explore their comparative benefits for patient outcomes.

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How effective is electrical stimulation in strengthening skeletal muscle? What stimulation parameters appear to be most effective?

Curious about the science behind neuromuscular electrical stimulation (NMES) in rehabilitation? In our latest article, we dive deep into how this established yet evolving technology effectively strengthens skeletal muscles.

From optimal stimulation parameters to clinical applications, discover why the "art" of electrical stimulation goes far beyond simply making muscles contract. Drawing from recent research and clinical evidence, we explore the mechanisms, effectiveness, and practical considerations for healthcare professionals working with neurological injuries and various rehabilitation scenarios.

Whether you're a clinician, researcher, or rehabilitation specialist, this comprehensive review offers valuable insights into maximizing NMES outcomes for patient care.

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Starting Small is Still Starting

Recovery and progress often seem daunting, especially when facing significant physical challenges or lifestyle changes. Whether you're an injured patient working through rehabilitation or someone who has fallen out of healthy habits, the gap between where you are and where you want to be can feel overwhelming. This article explores why taking that first small step - no matter how modest it may seem - is the most crucial part of any journey toward recovery or positive change. Drawing from both clinical experience with rehabilitation patients and personal insights about motivation, we'll examine how the compound effect of small, consistent actions can lead to remarkable transformations, even when the path ahead appears insurmountable.

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Electrical Stimulation and improved outcomes for Brachial Plexus injuries

In this article, we step back and consider how brachial plexus injuries are treated and then look at how forms of electrical stimulation might contribute to achieving the best clinical outcome.

Brachial plexus injuries present a complex challenge in medical practice, with the potential to produce significant functional impairment and reduced quality of life. Effective treatment requires a meticulous, multifaceted approach, combining surgical and non-surgical interventions tailored to the patient's specific needs. This article explores current treatment strategies, focusing on the potential role of electrical stimulation as a complementary therapy. By examining its applications and efficacy, we aim to highlight how this innovative technique could enhance recovery and optimise clinical outcomes for individuals affected by these injuries.

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